Effects of dietary approaches to stop hypertension diet versus usual dietary advice on glycemic indices in women at risk for cardiovascular disease; a randomized controlled clinical trial

Introduction Obesity has affected an approximated 300 million people in the worldwide (1). Its prevalence is expanding in both developed and developing countries. Type 2 diabetes may be the most destructive result that related to obesity (1). The risk of type 2 diabetes increases as body mass index (BMI) increases (2). The prevalence of type 2 diabetes is 3-7 times more in obese adults (3). The World Health Organization (WHO) has reported 44% of the diabetes is due to be overweight and obesity (4). Both obesity and type 2 diabetes are related to insulin resistance, although in normal conditions, some obese, insulin-resistant individuals do not become hyperglycemia, because of increasing insulin release to overcome the reduced efficiency of insulin action by the pancreatic islet β-cells, thus glucose tolerance remains normal (5). Dietary factors are important and potentially modifiable risk factors to prevent and control of diabetes (6). One of this diet which may be influenced on type 2 diabetes is the dietary approaches to stop hypertension (DASH) Implication for health policy/practice/research/medical education: Dietary factors are important and potentially modifiable risk factors to prevent and control of diabetes. As regard to a special component of dietary approaches to stop hypertension (DASH) diet, this diet may be influenced on type 2 diabetes, so this study was conducted to compare the effect of the DASH diet versus usual dietary advice (UDA) on fasting blood sugar (FBS), serum fasting insulin level (FINS), andhomeostasis model of insulin resistance (HOMA-IR). The result of this study suggested that DASH diet cannot improve glycemic markers compared to UDA. Please cite this paper as: Entezari MH, Hadi A, Kafeshani M. Effects of dietary approaches to stop hypertension diet versus usual dietary advice on glycemic indices in women at risk for cardiovascular disease; a randomized controlled clinical trial. J Renal Inj Prev. 2017;6(3):205-209. DOI: 10.15171/jrip.2017.39. Introduction: Diabetes is a global health problem. Dietary factors are important and potentially modifiable risk factors, to prevent and control of diabetes. One of these diets is the dietary approaches to stop hypertension (DASH) diet which may be influenced by risk factors for type 2 diabetes. Objectives: The main aim of this study was to investigate the effects of DASH diet versus usual dietary advice (UDA) on glycemic indices. Patients and Methods: In this randomized controlled clinical trial 44 healthy obese and overweight women were randomly assigned to the DASH diet or the UDA for 12 weeks. The fasting blood sugar (FBS), serum fasting insulin (FINS) level, and homeostasis model of insulin resistance (HOMA-IR) were measured at the first and end of the study. Results: There were no significant differences in any glycemic indices between two groups, however, FBS reduced in both DASH and UDA groups. Additionally, HOMA-IR and fasting concentration of insulin increased in UDA group. Conclusion: There was not the difference between recommendations to follow DASH dietary pattern or UDA in glycemic control. A R T I C L E I N F O